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1Department of Neuroscience, NBIC Center, Kurchatov Institute National Research Center, Moscow, Russia 2Department of Physics and Astronomy, Texas A&M University, College Station Texas, USA 3Physics Department, International Laser Center, M. V. Lomonosov Moscow State University, Russia 4P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia

Received 19 April 2011; revised 14 September 2011; published 6 December 2011

Suitably designed optical fibers are shown to offer a powerful tool for functional brain mapping, facilitating the detection of Cherenkov radiation generated by relativistic positrons from positron-emitting radionuclides. Fiber probes support a low-loss delivery of the high-intensity short-wavelength part of the Cherenkov spectrum, which is strongly absorbed by biotissues, and lower the threshold positron energy ε required for Cherenkov radiation relative to ε values typical of biotissues, thus enhancing the conversion of positron energy into Cherenkov radiation.

©2011 American Physical Society URL: http://link.aps.org/doi/10.1103/PhysRevE.84.061902 DOI: 10.1103/PhysRevE.84.061902 PACS: 87.57.-s

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