Neuroimmunology Continued-Detail

Source: wikipediahttp://en.wikipedia.org/wiki/NeuroimmunologyThe field of combining neurology and immunology.The study of "malfunction of either and or both systems that leads to disorders, and the physical, chemical, and environmental stressors that affect the two systems on a daily basis."In HSR we can find allowances for the use of environmental and social behavioral manipulation of the subject, the EPA has allowances for the use of chemicals and pharamachological agents."Neural targets that control thermogenesis, behavior, sleep, and mood can be affected by pro-inflammatory cytokines which are released by activated macrophages and monocytes during infection. Within the central nervous system production of cytokines has been detected as a result of brain injury, during viral and bacterial infections, and in neurodegenerative processes."thermogenics-heat creationcytokines-"are small cell-signaling protein molecules that are secreted by the glial cells of the nervous system and by numerous cells of the immune system and are a category of signaling molecules used extensively in intercellular communication" source wikipedia http://en.wikipedia.org/wiki/Cytokinemacrophages-white blood cellmonocytes-another kind of white blood cell""Neuroinflammation and neuroimmune activation have been shown to play a role in the etiology of a variety of neurological disorders such as stroke, Parkinson's and Alzheimer's disease, multiple sclerosis, pain, and AIDS-associated dementia. However, cytokines and chemokines also modulate CNS function in the absence of overt immunological, physiological, or psychological challenges. For example, cytokines and cytokine receptor inhibitors affect cognitive and emotional processes. Recent evidence suggests that immune molecules modulate brain systems differently across the lifespan."Wikipedia author quote from NIH
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