MIT; Introduction/Overview of Brain Disorders

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In their symposium introduction, Susan Hockfield and Mriganka Sur place MIT at the forefront of a revolution in neuroscience. Hockfield, a neuroscientist by training, recaps the evolution of the discipline at MIT, from its 1964 start in the Department of Psychology to the more recent establishment of the Department of Brain and Cognitive Sciences. These changes mirror the transformation of a field in which, says Hockfield, “at first you could do little more than make qualitative observations about behavior and only speculate about causes, to one that can examine brain function at the level of molecules and cell circuits; that can conduct quantitative experiments with genetically targeted model systems and can directly observe the living human brain in action.”We are now poised “for the first time in human history to deliver scientifically designed, rational therapies for some crippling disorders of the brain.” Hockfield credits MIT’s progress to “meta-experiments,” specifically collaborations among scientists and engineers, and the generosity of patrons.

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